Manipal Hospital Baner Performs Its First Precision Radiosurgery for Relapsed Brain AVM in Eloquent Brain Region

Cutting-Edge Radiosurgery Gives New Hope to Relapsed AVM Patient

Pune, May 2025:A 24-year-old suffering from relapsed  Arteriovenous Malformation (AVM) in brain area was successfully treated in Manipal Hospital Baner, Pune, using single-session Stereotactic Radiosurgery (SRS). Due to its location in an eloquent area of the brain, the lesion, which had previously been treated with GammaKnife in 2021, had recurred and posed a significant risk. Because the AVM, a tangled bundle of faulty blood vessels in the brain, was in an eloquent region important to necessary neurological functions, conventional neurosurgery was exceedingly risky.

Arteriosclerosis malformation, or AVM, is a blood vessel disorder wherein there is abnormal communication between arteries and venous via fragile and immature small vessels. It can occur anywhere in the body, including the brain. An AVM could end up in tissue damage and bleeding. There could be no symptoms at all until bleeding starts in the area where the abnormal vein-artery junction has formed. Often, this bleeding can be fatal or cause permanent damages like paralysis. AVMs are typically treated by removing surgically, reducing/ablating with Radiation, or stopping blood flow through an aberrant connection by Embolization.

Speaking about the case, Dr. Karan Chanchlani, Consultant – Radiation Oncology, Manipal Hospital, Baner, Pune, Said, “The complete dose was delivered in a single session with sub-millimeter accuracy. Meticulous planning was important since the patient had undergone GammaKnife therapy earlier without success. This was a technically challenging case since the AVM was located in a part of the brain that was very susceptible to neurological impairments after surgery. To precisely locate the nidus and determine the causes of the prior failure, we performed comprehensive MR with TOF sequences and Digital Subtraction Angiography considering the patient’s history of recurrence after Gamma Knife radiosurgery.  The patient underwent treatment with high-precision Stereotactic Radiosurgery (SRS), which delivered focused high dose of radiation with sub-millimeter accuracy in a short time. Most importantly, the entire procedure was non-invasive as we use Frameless systems for delivering our SRS plans. The post-procedure period was uncomplicated, and the patient is now stable, ambulatory, and recovering well.”

Mr. Anand Mote, Hospital Director, Manipal Hospital, Baner, Pune, Said, “We are proud to bring cutting-edge radiosurgical capabilities to our center, especially for cases where traditional approaches are limited. At Manipal Hospital Baner, providing safe, accurate, and efficient care is our top priority. Our dedication to patient-centered innovation, teamwork, and medical quality is demonstrated by the successful resolution of this AVM case.”